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NDB ID: NA1609    PDB ID: 4DR6 


Title:

CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS (HB8) 30S RIBOSOMAL SUBUNIT WITH CODON, NEAR-COGNATE TRANSFER RNA ANTICODON STEM-LOOP MISMATCHED AT THE FIRST CODON POSITION AND STREPTOMYCIN BOUND

Molecular Description:

PROTEIN/RNA Complex

Deposited:

2012-02-16

Released:

2012-11-14

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 5 nucleic acid sequences

Protein Sequence:

Click to show/hide 20 protein sequences

Primary Citation:

Demirci, H., Murphy, F., Murphy, E., Gregory, S.T., Dahlberg, A.E., Jogl, G.
A structural basis for streptomycin-induced misreading of the genetic code. 
Nat Commun, 4, pp. 1355 - 1355, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 402.6   b = 402.6   c = 174.9 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1554 for 213574 reflections in the resolution range 49.484 to 3.3 Ångstroms with Fobs >  1.99 sigma(Fobs) and with I >  0.0 sigma(I)