A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 8-Jul-2020 number of released structures: 10846
Search for released structures

NDB ID: NA2012    PDB ID: 4GZ1 


Title:

MUS MUSCULUS TDP2 REACTION PRODUCT (5'-PHOSPHORYLATED DNA)-MG2+ COMPLEX AT 1.5 ANGSTROMS RESOLUTION

Molecular Description:

Tyrosyl-DNA phosphodiesterase 2 (E.C.3.1.4.-)

Deposited:

2012-09-05

Released:

2012-10-31

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Schellenberg, M.J., Appel, C.D., Adhikari, S., Robertson, P.D., Ramsden, D.A., Williams, R.S.
Mechanism of repair of 5'-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2. 
Nat.Struct.Mol.Biol., 19, pp. 1363 - 1371, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 55.2   b = 69.139   c = 167.789 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1468 for 104060 reflections in the resolution range 30.073 to 1.5 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)