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NDB ID: 4PJO    PDB ID: 4PJO 


Title:

MINIMAL U1 SNRNP

Molecular Description:

SmD3
SmB (1-95)
SmD1 (1-85) plus N-terminal (GlySer)3 linker
SmD2
SmE
SmF (1-75)
SmG
U1-70k (1-59)
U1-C (1-61)/RNA Complex

Deposited:

2014-05-12

Released:

2014-12-31

Structural Keywords:

A DOUBLE HELIX, OPEN HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 9 protein sequences

Primary Citation:

Kondo, Y., Oubridge, C., van Roon, A.M., Nagai, K.
Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition. 
Elife, 4, pp. - , 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 120.359   b = 172.627   c = 256.322 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.20943 for 74960 reflections in the resolution range 70.0 to 3.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)