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NDB ID: 4PMW    PDB ID: 4PMW     NAKB(beta): 4PMW 


Title:

STRUCTURE OF MOUSE DIS3L2 IN COMPLEX WITH OLIGOU RNA SUBSTRATE

Molecular Description:

Dis3L2/RNA Complex

Deposited:

2014-05-22

Released:

2014-07-30

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Faehnle, C.R., Walleshauser, J., Joshua-Tor, L.
Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. 
Nature, 514, pp. 252 - 256, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 63.927   b = 96.075   c = 157.311 (Ångstroms)

α = 90.0   β = 98.75   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2046 for 39754 reflections in the resolution range 63.182 to 2.95 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)