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NDB ID: NA2990    PDB ID: 4Q9Q 


Title:

CRYSTAL STRUCTURE OF AN RNA APTAMER BOUND TO BROMO-LIGAND ANALOG IN COMPLEX WITH FAB

Molecular Description:

Fab BL3-6

Deposited:

2014-05-01

Released:

2014-06-18

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Huang, H., Suslov, N.B., Li, N.S., Shelke, S.A., Evans, M.E., Koldobskaya, Y., Rice, P.A., Piccirilli, J.A.
A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. 
Nat.Chem.Biol., 10, pp. 686 - 691, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 146.545   b = 79.676   c = 95.28 (Ångstroms)

α = 90.0   β = 111.51   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1837 for 37296 reflections in the resolution range 46.43 to 2.45 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)