NDB ID: NA3289    PDB ID: 4RQ5 

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Title:

HUMAN DNA POLYMERASE BETA WITH GAPPED DNA CONTAINING AN 8-OXO-7,8-DIHYDRO-GUANINE (8-OXOG)AND DATP SOAKED WITH MGCL2 FOR 60 S

Molecular Description:

DNA polymerase beta (E.C.2.7.7.7
4.2.99.-)

Deposited:

2014-10-31

Released:

2015-04-15

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Vyas, R., Reed, A.J., Tokarsky, E.J., Suo, Z.
Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography. 
J.Am.Chem.Soc., 137, pp. 5225 - 5230, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 49.212   b = 79.702   c = 55.384 (Ångstroms)

α = 90.0   β = 106.66   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.19975 for 16065 reflections in the resolution range 50.0 to 2.32 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

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Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

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