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NDB ID: 4TQR    PDB ID: 4TQR 


Title:

TERNARY COMPLEX OF Y-FAMILY DNA POLYMERASE DPO4 WITH (5'S)-8,5'-CYCLO-2'-DEOXYGUANOSINE AND DTTP

Molecular Description:

Sulfolobus solfataricus P2 DNA polymerase IV/DNA Complex

Deposited:

2014-06-11

Released:

2015-01-14

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Xu, W., Ouellette, A.M., Wawrzak, Z., Shriver, S.J., Anderson, S.M., Zhao, L.
Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling. 
Biochemistry, 54, pp. 639 - 651, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 58.537   b = 89.406   c = 112.39 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.183 for 81191 reflections in the resolution range 28.32 to 1.58 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)