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NDB ID: 4TVX    PDB ID: 4TVX 

Consolidated from the split entries: 1VY8, 1VY9

Title:

CRYSTAL STRUCTURE OF THE E. COLI CRISPR RNA-GUIDED SURVEILLANCE COMPLEX, CASCADE

Molecular Description:

Cse2
Cas7
Cas6e
Cas5e
Cse1/RNA Complex

Deposited:

2014-06-28

Released:

2014-08-13

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 5 protein sequences

Primary Citation:

Jackson, R.N., Golden, S.M., van Erp, P.B., Carter, J., Westra, E.R., Brouns, S.J., van der Oost, J., Terwilliger, T.C., Read, R.J., Wiedenheft, B.
Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli. 
Science, 345, pp. 1473 - 1479, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 200.851   b = 214.541   c = 217.383 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2342 for 148795 reflections in the resolution range 39.614 to 3.24 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)