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NDB ID: 4V7M    PDB ID: 4V7M 

Consolidated from the split entries: 3KNL, 3KNM, 3KNN, 3KNO

Title:

THE STRUCTURES OF CAPREOMYCIN BOUND TO THE 70S RIBOSOME.

Molecular Description:

70S Ribosome/Capreomycin IA

Deposited:

2009-11-12

Released:

2014-07-09

Nucleic Acid Sequence:

Click to show/hide 8 nucleic acid sequences

Protein Sequence:

Click to show/hide 51 protein sequences

Primary Citation:

Stanley, R.E., Blaha, G., Grodzicki, R.L., Strickler, M.D., Steitz, T.A.
The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. 
Nat.Struct.Mol.Biol., 17, pp. 289 - 293, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 210.355   b = 448.236   c = 631.156 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.218 for 661327 reflections in the resolution range 50.0 to 3.45 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)