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NDB ID: 4V7S    PDB ID: 4V7S 

Consolidated from the split entries: 3OAQ, 3OAR, 3OAS, 3OAT

Title:

CRYSTAL STRUCTURE OF THE E. COLI RIBOSOME BOUND TO TELITHROMYCIN.

Molecular Description:

Ribosome
telithromycin

Deposited:

2010-08-05

Released:

2014-07-09

Nucleic Acid Sequence:

Click to show/hide 5 nucleic acid sequences

Protein Sequence:

Click to show/hide 53 protein sequences

Primary Citation:

Dunkle, J.A., Xiong, L., Mankin, A.S., Cate, J.H.
Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. 
Proc.Natl.Acad.Sci.USA, 107, pp. 17152 - 17157, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 210.759   b = 433.272   c = 618.863 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1943 for 754750 reflections in the resolution range 85.218 to 3.2547 Ångstroms with Fobs >  0.02 sigma(Fobs) and with I >  0.0 sigma(I)