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NDB ID: 4X23    PDB ID: 4X23     NAKB: 4X23 


Title:

CRYSTAL STRUCTURE OF CENP-C IN COMPLEX WITH THE NUCLEOSOME CORE PARTICLE

Molecular Description:

HISTONE H3/CENP-A
HISTONE H4
HISTONE H2A
HISTONE H2B
VAL-ARG-ARG-SER-ASN-ARG-ILE-ARG-LEU-LYS-PRO-LEU-GLU-TYR-TRP-ARG-GLY-GLU-ARG-ILE-ASP-TYR/DNA Complex

Deposited:

2014-11-25

Released:

2014-12-10

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 5 protein sequences

Primary Citation:

Kato, H., Jiang, J.S., Zhou, B.R., Rozendaal, M., Feng, H., Ghirlando, R., Xiao, T.S., Straight, A.F., Bai, Y.
A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C. 
Science, 340, pp. 1110 - 1113, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 102.994   b = 176.102   c = 208.846 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2382 for 48623 reflections in the resolution range 49.543 to 3.5 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)