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NDB ID: 4X9J    PDB ID: 4X9J 


Title:

EGR-1 WITH DOUBLY METHYLATED DNA

Molecular Description:

EGR-1/DNA Complex

Deposited:

2014-12-11

Released:

2015-05-13

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Zandarashvili, L., White, M.A., Esadze, A., Iwahara, J.
Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1. 
Febs Lett., 589, pp. 1748 - 1753, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 44.009   b = 55.989   c = 128.952 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1738 for 46626 reflections in the resolution range 27.357 to 1.412 Ångstroms with Fobs >  1.37 sigma(Fobs) and with I >  0.0 sigma(I)