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NDB ID: 4XBF    PDB ID: 4XBF     NAKB(beta): 4XBF 


Title:

STRUCTURE OF LSD1:COREST IN COMPLEX WITH SSRNA

Molecular Description:

Lysine-specific histone demethylase 1A/REST corepressor 1/RNA Complex

Deposited:

2014-12-16

Released:

2016-04-27

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Hirschi, A., Martin, W.J., Luka, Z., Loukachevitch, L.V., Reiter, N.J.
G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme. 
RNA, 22, pp. 1250 - 1260, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 2 2 2

Cell Constants:

a = 121.073   b = 178.411   c = 234.676 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.202 for 62268 reflections in the resolution range 49.018 to 2.803 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)