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NDB ID: 4XQ8    PDB ID: 4XQ8 


Title:

HUMAN DNA POLYMERASE LAMBDA- MGDATP BINARY COMPLEX AND COMPLEX WITH 6 PAIRED DNA

Molecular Description:

DNA polymerase lambda/DNA Complex

Deposited:

2015-01-19

Released:

2016-02-24

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Liu, M.S., Tsai, H.Y., Liu, X.X., Ho, M.C., Wu, W.J., Tsai, M.D.
Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda 
J.Am.Chem.Soc., 138, pp. 2389 - 2398, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 83.743   b = 83.743   c = 398.746 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.187 for 17909 reflections in the resolution range 27.411 to 2.798 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)