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NDB ID: 4XRM    PDB ID: 4XRM 


Title:

HOMODIMER OF TALE TYPE HOMEOBOX TRANSCRIPTION FACTOR MEIS1 COMPLEXES WITH SPECIFIC DNA

Molecular Description:

MEIS1/DNA Complex

Deposited:

2015-01-21

Released:

2015-11-04

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Jolma, A., Yin, Y., Nitta, K.R., Dave, K., Popov, A., Taipale, M., Enge, M., Kivioja, T., Morgunova, E., Taipale, J.
DNA-dependent formation of transcription factor pairs alters their binding specificity. 
Nature, 527, pp. 384 - 388, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 2 2 2

Cell Constants:

a = 70.62   b = 79.28   c = 98.97 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1773 for 35951 reflections in the resolution range 19.83 to 1.6 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)