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NDB ID: 4XUJ    PDB ID: 4XUJ 


Title:

NUCLEOSOME CORE PARTICLE CONTAINING ADDUCTS FROM TREATMENT WITH A THIOMORPHOLINE-SUBSTITUTED [(ETA-6-P-CYMENE)RU(3-HYDROXY-2-PYRIDONE)CL] COMPOUND

Molecular Description:

Histone H3.2
Histone H4
Histone H2A
Histone H2B 1.1/DNA Complex

Deposited:

2015-01-26

Released:

2016-01-27

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Hanif, M., Meier, S.M., Adhireksan, Z., Henke, H., Martic, S., Labib, M., Kandioller, W., Jakupec, M.A., Kraatz, H.B., Davey, C.A., Keppler, B.K., Hartinger, C.G.
Contrasting Cytotoxicity and Reactivity of RuII-Arene Complexes of Morpholine vs Thiomorpholine Substituted 3-Hydroxy-2-pyridone Ligands
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 106.426   b = 109.754   c = 181.277 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.265 for 33808 reflections in the resolution range 93.89 to 3.18 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)