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NDB ID: 4XUS    PDB ID: 4XUS 


Title:

CRYSTAL STRUCTURE OF THE PRE-CATALYTIC TERNARY COMPLEX OF DNA POLYMERASE LAMBDA WITH A TEMPLATING A AND AN INCOMING DTTP

Molecular Description:

Polymerase Lambda/DNA Complex

Deposited:

2015-01-26

Released:

2016-02-03

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Burak, M.J., Guja, K.E., Garcia-Diaz, M.
Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda. 
Nucleic Acids Res., 43, pp. 8089 - 8099, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 56.05   b = 63.28   c = 141.06 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the BUSTER program. The R value is 0.1898 for 17565 reflections in the resolution range 41.96 to 2.4 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)