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NDB ID: 4Y52    PDB ID: 4Y52 


Title:

CRYSTAL STRUCTURE OF 5-CARBOXYCYTOSINE RECOGNITION BY RNA POLYMERASE II DURING TRANSCRIPTION ELONGATION.

Molecular Description:

DNA-directed RNA polymerase II/DNA

Deposited:

2015-02-11

Released:

2015-07-15

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 10 protein sequences

Primary Citation:

Wang, L., Zhou, Y., Xu, L., Xiao, R., Lu, X., Chen, L., Chong, J., Li, H., He, C., Fu, X.D., Wang, D.
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex. 
Nature, 523, pp. 621 - 625, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 166.703   b = 221.644   c = 192.41 (Ångstroms)

α = 90.0   β = 100.35   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2027 for 81638 reflections in the resolution range 49.273 to 3.5 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)