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NDB ID: 4Y7N    PDB ID: 4Y7N 


Title:

THE STRUCTURE INSIGHT INTO 5-CARBOXYCYTOSINE RECOGNITION BY RNA POLYMERASE II DURING TRANSCRIPTION ELONGATION.

Molecular Description:

DNA-directed RNA polymerase II subunit RPB1
DNA-directed RNA polymerase II subunit RPB2
DNA-directed RNA polymerase II subunit RPB3
DNA-directed RNA polymerases I
II
and III subunit RPABC1
??DNA-directed RNA polymerases I
II
and III subunit RPABC2
DNA-directed RNA polymerases I
II
and III subunit RPABC3
DNA-directed RNA polymerase II subunit RPB9
DNA-directed RNA polymerases I
II
and III subunit RPABC5
DNA-directed RNA polymerase II subunit RPB11
DNA-directed RNA polymerases I
II
and III subunit RPABC4/DNA Complex

Deposited:

2015-02-15

Released:

2015-07-15

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 10 protein sequences

Primary Citation:

Wang, L., Zhou, Y., Xu, L., Xiao, R., Lu, X., Chen, L., Chong, J., Li, H., He, C., Fu, X.D., Wang, D.
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex. 
Nature, 523, pp. 621 - 625, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 168.181   b = 222.614   c = 192.829 (Ångstroms)

α = 90.0   β = 101.59   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.209 for 105636 reflections in the resolution range 48.88 to 3.3 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)