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NDB ID: NA1771    PDB ID: 4F5R 


Title:

OPEN AND CLOSED TERNARY COMPLEX OF R283K DNA POLYMERASE BETA WITH A DCTP ANALOG IN THE SAME ASYMMETRIC UNIT

Molecular Description:

DNA polymerase beta (E.C.2.7.7.7
4.2.99.-)/DNA

Deposited:

2012-05-13

Released:

2012-12-12

Structural Keywords:

A DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Freudenthal, B.D., Beard, W.A., Wilson, S.H.
Structures of dNTP Intermediate States during DNA Polymerase Active Site Assembly. 
Structure, 20, pp. 1829 - 1837, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 55.028   b = 79.446   c = 102.09 (Ångstroms)

α = 90.0   β = 96.96   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2122 for 74621 reflections in the resolution range 21.36 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)