A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 18-May-2022 number of released structures: 12082
Search for released structures

NDB ID: NA2305    PDB ID: 4JV1 


Title:

TERNARY COMPLEX OF GAMMA-OHPDG ADDUCT MODIFIED DNA WITH DNA (-1 PRIMER) POLYMERASE IV AND INCOMING DGTP

Molecular Description:

DNA polymerase IV (E.C.2.7.7.7)

Deposited:

2013-03-25

Released:

2013-08-28

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Shanmugam, G., Minko, I.G., Banerjee, S., Christov, P.P., Kozekov, I.D., Rizzo, C.J., Lloyd, R.S., Egli, M., Stone, M.P.
Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4. 
Chem.Res.Toxicol., 26, pp. 1348 - 1360, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 93.274   b = 102.183   c = 52.727 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.218 for 23031 reflections in the resolution range 41.87 to 2.3 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)