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NDB ID: NA2485    PDB ID: 4L0Y 


Title:

CRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 1)

Molecular Description:

Runt-related transcription factor 1
Protein C-ets-1/DNA complex

Deposited:

2013-06-01

Released:

2014-03-26

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Shrivastava, T., Mino, K., Babayeva, N.D., Baranovskaya, O.I., Rizzino, A., Tahirov, T.H.
Structural basis of Ets1 activation by Runx1. 
Leukemia, 28, pp. 2040 - 2048, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 102.622   b = 138.945   c = 98.439 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.225 for 23493 reflections in the resolution range 29.67 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)