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NDB ID: NA2588    PDB ID: 4LEY 


Title:

STRUCTURE OF MOUSE CGAS BOUND TO 18 BP DNA

Molecular Description:

Cyclic GMP-AMP synthase (E.C.2.7.7.-)

Deposited:

2013-06-26

Released:

2013-12-25

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Li, X., Shu, C., Yi, G., Chaton, C.T., Shelton, C.L., Diao, J., Zuo, X., Kao, C.C., Herr, A.B., Li, P.
Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization. 
Immunity, 39, pp. 1019 - 1031, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 78.377   b = 145.895   c = 100.963 (Ångstroms)

α = 90.0   β = 90.07   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.0 for 78261 reflections in the resolution range 40.773 to 2.5 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)