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NDB ID: NA2659    PDB ID: 4MFA 


Title:

STRUCTURE OF HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA CONTAINING A MISMATCHED TEMPLATE O6MG AND INCOMING TTP

Molecular Description:

DNA polymerase beta (E.C.2.7.7.7
4.2.99.-)

Deposited:

2013-08-27

Released:

2014-08-27

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Koag, M.C., Min, K., Monzingo, A.F., Lee, S.
Structures of human DNA polymerase beta inserting bases opposite templating O6MG
To be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 54.971   b = 79.662   c = 55.001 (Ångstroms)

α = 90.0   β = 106.68   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2155 for 20618 reflections in the resolution range 30.0 to 2.27 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)