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NDB ID: 5BS8    PDB ID: 5BS8 


Title:

CRYSTAL STRUCTURE OF A TOPOISOMERASE II COMPLEX

Molecular Description:

DNA gyrase subunit A
DNA gyrase subunit B/DNA Complex

Deposited:

2015-06-01

Released:

2016-03-02

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Blower, T.R., Williamson, B.H., Kerns, R.J., Berger, J.M.
Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis. 
Proc.Natl.Acad.Sci.USA, 113, pp. 1706 - 1713, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 108.357   b = 83.07   c = 129.856 (Ångstroms)

α = 90.0   β = 109.33   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1976 for 83480 reflections in the resolution range 102.252 to 2.399 Ångstroms with Fobs >  1.89 sigma(Fobs) and with I >  0.0 sigma(I)