A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 23-Sep-2020 number of released structures: 10967
Search for released structures

NDB ID: 5BT2    PDB ID: 5BT2 


Title:

MECP2 MBD DOMAIN (A140V) IN COMPLEX WITH METHYLATED DNA

Molecular Description:

Methyl-CpG-binding protein 2/DNA Complex

Deposited:

2015-06-02

Released:

2016-08-17

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chia, J.Y., Tan, W.S., Ng, C.L., Hu, N.J., Foo, H.L., Ho, K.L.
A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence. 
Sci Rep, 6, pp. 31210 - 31210, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 78.66   b = 53.49   c = 65.78 (Ångstroms)

α = 90.0   β = 132.47   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.1773 for 9955 reflections in the resolution range 48.5 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)