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NDB ID: 5BTI    PDB ID: 5BTI 


Title:

CRYSTAL STRUCTURE OF A TOPOISOMERASE II COMPLEX

Molecular Description:

DNA gyrase subunit A
DNA gyrase subunit B/DNA Complex

Deposited:

2015-06-03

Released:

2016-03-02

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Blower, T.R., Williamson, B.H., Kerns, R.J., Berger, J.M.
Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis. 
Proc.Natl.Acad.Sci.USA, 113, pp. 1706 - 1713, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 108.39   b = 83.28   c = 129.701 (Ångstroms)

α = 90.0   β = 108.73   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2158 for 141330 reflections in the resolution range 49.429 to 2.501 Ångstroms with Fobs >  1.09 sigma(Fobs) and with I >  0.0 sigma(I)