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NDB ID: 5C0X    PDB ID: 5C0X 


Title:

STRUCTURE OF A 12-SUBUNIT NUCLEAR EXOSOME COMPLEX BOUND TO STRUCTURED RNA

Molecular Description:

Exosome complex component RRP45
Exosome complex component SKI6
Exosome complex component RRP43
Exosome complex component RRP46
Exosome complex component RRP42
Exosome complex component MTR3
Exosome complex component RRP40
Exosome complex component RRP4
Exosome complex component CSL4
Exosome complex exonuclease DIS3
Exosome complex exonuclease RRP6/RNA Complex

Deposited:

2015-06-12

Released:

2015-08-05

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 11 protein sequences

Primary Citation:

Makino, D.L., Schuch, B., Stegmann, E., Baumgartner, M., Basquin, C., Conti, E.
RNA degradation paths in a 12-subunit nuclear exosome complex. 
Nature, 524, pp. 54 - 58, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 106.15   b = 177.39   c = 299.9 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2949 for 45723 reflections in the resolution range 57.887 to 3.812 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)