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NDB ID: 5CBZ    PDB ID: 5CBZ 


Title:

ANCMR DNA BINDING DOMAIN - (+)GRE COMPLEX

Molecular Description:

Mineralocorticoid receptor/DNA Complex

Deposited:

2015-07-01

Released:

2015-12-23

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hudson, W.H., Kossmann, B.R., de Vera, I.M., Chuo, S.W., Weikum, E.R., Eick, G.N., Thornton, J.W., Ivanov, I.N., Kojetin, D.J., Ortlund, E.A.
Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space. 
Proc.Natl.Acad.Sci.USA, 113, pp. 326 - 331, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 47.532   b = 81.15   c = 116.416 (Ångstroms)

α = 90.0   β = 96.8   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1974 for 44737 reflections in the resolution range 25.003 to 2.2 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)