A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 18-Sep-2019 number of released structures: 10387
Search for released structures

NDB ID: 5CCW    PDB ID: 5CCW 


Title:

STRUCTURE OF THE COMPLEX OF A HUMAN TELOMERIC DNA WITH AU(CAFFEIN-2-YLIDENE)2

Molecular Description:

human telomeric DNA

Deposited:

2015-07-02

Released:

2016-03-16

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Bazzicalupi, C., Ferraroni, M., Papi, F., Massai, L., Bertrand, B., Messori, L., Gratteri, P., Casini, A.
Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation. 
Angew.Chem.Int.Ed.Engl., 55, pp. 4256 - 4259, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 21 21 21

Cell Constants:

a = 47.129   b = 51.286   c = 58.768 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2271 for 5512 reflections in the resolution range 30.0 to 1.89 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)