A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 8-Jul-2020 number of released structures: 10846
Search for released structures

NDB ID: 5CD1    PDB ID: 5CD1 


Title:

STRUCTURE OF AN ASYMMETRIC TETRAMER OF HUMAN TRNA M1A58 METHYLTRANSFERASE IN A COMPLEX WITH SAH AND TRNA3LYS

Molecular Description:

tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6/RNA Complex

Deposited:

2015-07-02

Released:

2015-11-04

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Finer-Moore, J., Czudnochowski, N., O'Connell, J.D., Wang, A.L., Stroud, R.M.
Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target. 
J.Mol.Biol., 427, pp. 3862 - 3876, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 128.24   b = 137.44   c = 157.59 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2337 for 32711 reflections in the resolution range 59.392 to 3.6 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)