NDB ID: 5CDR    PDB ID: 5CDR 

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Title:

2.65 STRUCTURE OF S.AUREUS DNA GYRASE AND ARTIFICIALLY NICKED DNA

Molecular Description:

DNA gyrase subunit A
DNA gyrase subunit B/DNA Complex

Deposited:

2015-07-04

Released:

2015-12-16

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Chan, P.F., Srikannathasan, V., Huang, J., Cui, H., Fosberry, A.P., Gu, M., Hann, M.M., Hibbs, M., Homes, P., Ingraham, K., Pizzollo, J., Shen, C., Shillings, A.J., Spitzfaden, C.E., Tanner, R., Theobald, A.J., Stavenger, R.A., Bax, B.D., Gwynn, M.N.
Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin. 
Nat Commun, 6, pp. 10048 - 10048, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 93.395   b = 93.395   c = 410.583 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the BUSTER-TNT program. The R value is 0.1888 for 58050 reflections in the resolution range 39.74 to 2.65 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

Download Data:

Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

XML | Complete with coordinates (xml format, GNU compressed(.gz))

XML | Coordinates only (xml format, GNU compressed(.gz))

XML | Header only (xml format, GNU compressed(.gz))