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NDB ID: 5D8L    PDB ID: 5D8L 


Title:

HUMAN HSF2 DNA BINDING DOMAIN IN COMPLEX WITH 3-SITE HSE DNA AT 2.1 ANGSTROMS RESOLUTION

Molecular Description:

Heat shock factor protein 2/DNA Complex

Deposited:

2015-08-17

Released:

2016-01-06

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Jaeger, A.M., Pemble, C.W., Sistonen, L., Thiele, D.J.
Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. 
Nat.Struct.Mol.Biol., 23, pp. 147 - 154, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 40.174   b = 47.14   c = 109.587 (Ångstroms)

α = 82.82   β = 90.03   γ = 64.75 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2199 for 38940 reflections in the resolution range 24.41 to 2.069 Ångstroms with Fobs >  1.96 sigma(Fobs) and with I >  0.0 sigma(I)