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NDB ID: 5DOY    PDB ID: 5DOY     NAKB(beta): 5DOY 


Title:

CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ANTIBIOTIC HYGROMYCIN A, MRNA AND THREE TRNAS IN THE A, P AND E SITES AT 2.6A RESOLUTION

Molecular Description:

Deposited:

2015-09-11

Released:

2015-12-30

Nucleic Acid Sequence:

Click to show/hide 6 nucleic acid sequences

Protein Sequence:

Click to show/hide 49 protein sequences

Primary Citation:

Polikanov, Y.S., Starosta, A.L., Juette, M.F., Altman, R.B., Terry, D.S., Lu, W., Burnett, B.J., Dinos, G., Reynolds, K.A., Blanchard, S.C., Steitz, T.A., Wilson, D.N.
Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A. 
Mol.Cell, 58, pp. 832 - 844, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 208.39   b = 444.58   c = 619.2 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2358 for 1724898 reflections in the resolution range 361.136 to 2.6 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)