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NDB ID: 5E6B    PDB ID: 5E6B 


Title:

GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - RELB NF-KB RESPONSE ELEMENT COMPLEX

Molecular Description:

Glucocorticoid receptor/DNA Complex

Deposited:

2015-10-09

Released:

2017-02-08

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hudson, W.H., Vera, I.M.S., Nwachukwu, J.C., Weikum, E.R., Herbst, A.G., Yang, Q., Bain, D.L., Nettles, K.W., Kojetin, D.J., Ortlund, E.A.
Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements. 
Nat Commun, 9, pp. 1337 - 1337, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 39.185   b = 97.045   c = 103.329 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2058 for 19089 reflections in the resolution range 32.459 to 2.25 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)