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NDB ID: 5EV1    PDB ID: 5EV1 


Title:

STRUCTURE I OF INTACT U2AF65 RECOGNIZING A 3' SPLICE SITE SIGNAL

Molecular Description:

Splicing factor U2AF 65 kDa subunit/RNA Complex

Deposited:

2015-11-19

Released:

2016-02-24

Structural Keywords:

, LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Agrawal, A.A., Salsi, E., Chatrikhi, R., Henderson, S., Jenkins, J.L., Green, M.R., Ermolenko, D.N., Kielkopf, C.L.
An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. 
Nat Commun, 7, pp. 10950 - 10950, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 62.052   b = 114.241   c = 59.418 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1778 for 12124 reflections in the resolution range 32.456 to 2.037 Ångstroms with Fobs >  0.89 sigma(Fobs) and with I >  0.0 sigma(I)