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NDB ID: 5EWF    PDB ID: 5EWF 


Title:

TERNARY COMPLEX OF HUMAN DNA POLYMERASE ETA INSERTING RCTP OPPOSITE AN 8-OXODEOXYGUANOSINE LESION

Molecular Description:

DNA polymerase eta/DNA Complex

Deposited:

2015-11-20

Released:

2016-01-13

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Su, Y., Egli, M., Guengerich, F.P.
Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. 
J.Biol.Chem., 291, pp. 3747 - 3756, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 99.124   b = 99.124   c = 81.384 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1812 for 43080 reflections in the resolution range 42.922 to 1.782 Ångstroms with Fobs >  0.12 sigma(Fobs) and with I >  0.0 sigma(I)