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NDB ID: 5F9N    PDB ID: 5F9N 


Title:

CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N2-ETHENODEOXYGUANOSINE LESION

Molecular Description:

DNA polymerase eta/DNA Complex

Deposited:

2015-12-09

Released:

2016-12-21

Structural Keywords:

B DOUBLE HELIX, FLIPPED OUT BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Patra, A., Egli, M.
Bypass of the 1, N2-Ethenodeoxyguanosine Lesion by Human DNA Polymerase Eta
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 99.08   b = 99.08   c = 81.89 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1604 for 22348 reflections in the resolution range 42.9 to 2.23 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)