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NDB ID: 5INO    PDB ID: 5INO 


Title:

HUMAN TDP2 REACTION PRODUCT (5'-PHOSPHORYLATED DNA)-MG2+ COMPLEX

Molecular Description:

Tyrosyl-DNA phosphodiesterase 2/DNA Complex

Deposited:

2016-03-07

Released:

2016-04-27

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Schellenberg, M.J., Perera, L., Strom, C.N., Waters, C.A., Monian, B., Appel, C.D., Vilas, C.K., Williams, J.G., Ramsden, D.A., Williams, R.S.
Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. 
Nucleic Acids Res., 44, pp. 3829 - 3844, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31

Cell Constants:

a = 69.663   b = 69.663   c = 120.677 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.216 for 10757 reflections in the resolution range 34.832 to 3.205 Ångstroms with Fobs >  1.98 sigma(Fobs) and with I >  0.0 sigma(I)