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NDB ID: 5ITH    PDB ID: 5ITH 


Title:

TIA-1 RRM2 RECOGNITION OF TARGET OLIGONUCLEOTIDE

Molecular Description:

Nucleolysin TIA-1 isoform p40/DNA Complex

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Waris, S., Garcia-Maurino, S.M., Sivakumaran, A., Beckham, S.A., Loughlin, F.E., Gorospe, M., Diaz-Moreno, I., Wilce, M.C.J., Wilce, J.A.
TIA-1 RRM23 binding and recognition of target oligonucleotides. 
Nucleic Acids Res., 45, pp. 4944 - 4957, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65

Cell Constants:

a = 45.43   b = 45.43   c = 84.9 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.8.4_1496) program. The R value is 0.2293 for 4374 reflections in the resolution range 22.974 to 2.31 Ångstroms with Fobs >  1.38 sigma(Fobs) and with I >  0.0 sigma(I)