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NDB ID: 5J5B    PDB ID: 5J5B 


Title:

STRUCTURE OF THE WT E COLI RIBOSOME BOUND TO TETRACYCLINE

Molecular Description:

ribosomal protein L10/RNA Complex

Deposited:

2016-04-01

Released:

2016-07-27

Nucleic Acid Sequence:

Click to show/hide 4 nucleic acid sequences

Protein Sequence:

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Primary Citation:

Cocozaki, A.I., Altman, R.B., Huang, J., Buurman, E.T., Kazmirski, S.L., Doig, P., Prince, D.B., Blanchard, S.C., Cate, J.H., Ferguson, A.D.
Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. 
Proc.Natl.Acad.Sci.USA, 113, pp. 8188 - 8193, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 212.31   b = 434.58   c = 624.92 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the BUSTER-TNT program. The R value is 0.209 for 36007 reflections in the resolution range 48.16 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)