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NDB ID: 5K5H    PDB ID: 5K5H 


Title:

HOMO SAPIENS CCCTC-BINDING FACTOR (CTCF) ZNF4-7 AND DNA COMPLEX STRUCTURE

Molecular Description:

Transcriptional repressor CTCF/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hashimoto, H., Wang, D., Horton, J.R., Zhang, X., Corces, V.G., Cheng, X.
Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. 
Mol. Cell, 66, pp. 711 - 720.e3, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 52.8   b = 52.8   c = 166.17 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2395 for 44172 reflections in the resolution range 50.321 to 3.108 Ångstroms with Fobs >  1.38 sigma(Fobs) and with I >  0.0 sigma(I)