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NDB ID: 5K5I    PDB ID: 5K5I 


Title:

HOMO SAPIENS CCCTC-BINDING FACTOR (CTCF) ZNF5-8 AND DNA COMPLEX STRUCTURE IN SPACE GROUP P65

Molecular Description:

Transcriptional repressor CTCF/DNA Complex

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hashimoto, H., Wang, D., Horton, J.R., Zhang, X., Corces, V.G., Cheng, X.
Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. 
Mol. Cell, 66, pp. 711 - 720.e3, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65

Cell Constants:

a = 45.075   b = 45.075   c = 260.45 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2198 for 30205 reflections in the resolution range 23.247 to 2.19 Ångstroms with Fobs >  1.43 sigma(Fobs) and with I >  0.0 sigma(I)