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NDB ID: 5K97    PDB ID: 5K97 


Title:

FLAP ENDONUCLEASE 1 (FEN1) D233N WITH CLEAVED PRODUCT FRAGMENT AND SM3+

Molecular Description:

Flap endonuclease 1/DNA Complex

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 4 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Tsutakawa, S.E., Thompson, M.J., Arvai, A.S., Neil, A.J., Shaw, S.J., Algasaier, S.I., Kim, J.C., Finger, L.D., Jardine, E., Gotham, V.J.B., Sarker, A.H., Her, M.Z., Rashid, F., Hamdan, S.M., Mirkin, S.M., Grasby, J.A., Tainer, J.A.
Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. 
Nat Commun, 8, pp. 15855 - 15855, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 105.236   b = 105.236   c = 104.548 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1843 for 74847 reflections in the resolution range 34.849 to 2.102 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)