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NDB ID: 5KL7    PDB ID: 5KL7 


Title:

WILMS TUMOR PROTEIN (WT1) ZNF2-4Q369R IN COMPLEX WITH CARBOXYLATED DNA

Molecular Description:

Wilms tumor protein/DNA Complex

Deposited:

2016-06-23

Released:

2016-09-14

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hashimoto, H., Zhang, X., Zheng, Y., Wilson, G.G., Cheng, X.
Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. 
Nucleic Acids Res., 44, pp. 10165 - 10176, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 67.458   b = 77.797   c = 35.683 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1652 for 26017 reflections in the resolution range 29.231 to 1.579 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)