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NDB ID: 5KRB    PDB ID: 5KRB 


Title:

GCNF DNA BINDING DOMAIN - OCT4 DR0 COMPLEX

Molecular Description:

Nuclear receptor subfamily 6 group A member 1/DNA Complex

Deposited:

2016-07-07

Released:

2016-11-09

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Weikum, E.R., Tuntland, M.L., Murphy, M.N., Ortlund, E.A.
A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1). 
J. Mol. Biol., 428, pp. 4981 - 4992, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 53.649   b = 69.469   c = 84.536 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2183 for 18228 reflections in the resolution range 37.944 to 2.101 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)