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NDB ID: 5KT6    PDB ID: 5KT6 


Title:

TERANRY COMPLEX OF HUMAN DNA POLYMERASE IOTA(1-445) INSERTING DCMPNPP OPPOSITE TEMPLATE G IN THE PRESENCE OF MG2+

Molecular Description:

DNA polymerase iota/DNA Complex

Deposited:

2016-07-11

Released:

2016-08-31

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Choi, J.Y., Patra, A., Yeom, M., Lee, Y.S., Zhang, Q., Egli, M., Guengerich, F.P.
Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota. 
J.Biol.Chem., 291, pp. 21063 - 21073, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 98.269   b = 98.269   c = 201.656 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2059 for 7517 reflections in the resolution range 47.738 to 3.54 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)