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NDB ID: 5L0M    PDB ID: 5L0M 


Title:

HLRH-1 DNA BINDING DOMAIN - 12BP OCT4 PROMOTER COMPLEX

Molecular Description:

Nuclear receptor subfamily 5 group A member 2/DNA Complex

Deposited:

2016-07-27

Released:

2016-11-09

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Weikum, E.R., Tuntland, M.L., Murphy, M.N., Ortlund, E.A.
A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1). 
J. Mol. Biol., 428, pp. 4981 - 4992, 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43

Cell Constants:

a = 40.931   b = 40.931   c = 105.055 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.158 for 8789 reflections in the resolution range 28.943 to 2.197 Ångstroms with Fobs >  1.38 sigma(Fobs) and with I >  0.0 sigma(I)