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NDB ID: 5MCT    PDB ID: 5MCT 


Title:

NEW INSIGHTS INTO THE ROLE OF DNA SHAPE ON ITS RECOGNITION BY P53 PROTEINS (COMPLEX P53DBD-LHG1)

Molecular Description:

Cellular tumor antigen p53/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Golovenko, D., Brauning, B., Vyas, P., Haran, T.E., Rozenberg, H., Shakked, Z.
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. 
Structure, 26, pp. 1237 - 1250.e6, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 137.486   b = 49.46   c = 68.503 (Ångstroms)

α = 90.0   β = 93.63   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1466 for 79745 reflections in the resolution range 46.529 to 1.446 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)