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NDB ID: 5MCW    PDB ID: 5MCW     NAKB(beta): 5MCW 


Title:

NEW INSIGHTS INTO THE ROLE OF DNA SHAPE ON ITS RECOGNITION BY P53 PROTEINS (COMPLEX P53DBD-LWC2)

Molecular Description:

Cellular tumor antigen p53/DNA Complex

Deposited:

2016-11-10

Released:

2018-06-13

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Golovenko, D., Brauning, B., Vyas, P., Haran, T.E., Rozenberg, H., Shakked, Z.
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. 
Structure, 26, pp. 1237 - 1250.e6, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 111.403   b = 68.408   c = 69.68 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2024 for 40244 reflections in the resolution range 48.815 to 1.897 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)